The NUF2 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to NUF2. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The NUF2 antibody has been validated for the following applications: EIA, Immunoassay, Precipitation, ELISA, Immunoprecipitation, and Western Blot.
Description
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity(PubMed:12438418, PubMed:14654001, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:17535814). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore(PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules(PubMed:23085020)